Conversion of Human Umbilical Cord Mesenchymal Stem Cells in Wharton’s Jelly to Dopamine Neurons Mediated by the Lmx1a and Neurturin In Vitro: Potential Therapeutic Application for Parkinson’s Disease in a Rhesus Monkey Model

hUC-MSCs hold great promise in vitro neuronal differentiation and therapy for neurodegenerative disorders including Parkinson’s disease. Recent studies provided that Lmx1α play an important role in the midbrain dopamine cells differentiation. Neurturin is desired candidate gene for providing a neuro...

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Detalles Bibliográficos
Autores principales: Yan, Min, Sun, Maosheng, Zhou, Yan, Wang, Wanpu, He, Zhanlong, Tang, Donghong, Lu, Shuaiyao, Wang, Xiaonan, Li, Song, Wang, Wenju, Li, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665802/
https://www.ncbi.nlm.nih.gov/pubmed/23724014
http://dx.doi.org/10.1371/journal.pone.0064000

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