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The Experimental Treatment of Corneal Graft Rejection with the Interleukin-1 Receptor Antagonist (IL-1ra) Gene

PURPOSE: To investigate the protective effects of interleukin-1 receptor antagonist (IL-1ra) gene transfer in a rat model of corneal graft rejection. METHODS: We constructed a recombinant plasmid (pcDNA3.1-hIL-1ra) with high IL-1ra expression in eukaryotic cells. Using a Wistar-SD rat model of corne...

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Detalles Bibliográficos
Autores principales:	Yuan, Jin, Liu, Yi, Huang, Weilan, Zhou, Shiyou, Ling, Shiqi, Chen, Jiaqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665808/ https://www.ncbi.nlm.nih.gov/pubmed/23723965 http://dx.doi.org/10.1371/journal.pone.0060714

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