PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

Small cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis. Expression array analysis of 23 SCLC cases and 42 normal tissues revealed that EZH2 and other PRC2 members were highly expressed in SCLC. ChIP-seq for H3K27me3 suggested that genes with H3K27me3(+) in SCLC were extended n...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Teruyuki, Kaneda, Atsushi, Tsuji, Shingo, Isagawa, Takayuki, Yamamoto, Shogo, Fujita, Takanori, Yamanaka, Ryota, Tanaka, Yukiko, Nukiwa, Toshihiro, Marquez, Victor E., Ishikawa, Yuichi, Ichinose, Masakazu, Aburatani, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665955/
https://www.ncbi.nlm.nih.gov/pubmed/23714854
http://dx.doi.org/10.1038/srep01911

Ejemplares similares

Ejemplares similares