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Digital optical phase conjugation for delivering two-dimensional images through turbid media

Optical transmission through complex media such as biological tissue is fundamentally limited by multiple light scattering. Precise control of the optical wavefield potentially holds the key to advancing a broad range of light-based techniques and applications for imaging or optical delivery. We pre...

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Autores principales: Hillman, Timothy R., Yamauchi, Toyohiko, Choi, Wonshik, Dasari, Ramachandra R., Feld, Michael S., Park, YongKeun, Yaqoob, Zahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665964/
https://www.ncbi.nlm.nih.gov/pubmed/23714766
http://dx.doi.org/10.1038/srep01909
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author Hillman, Timothy R.
Yamauchi, Toyohiko
Choi, Wonshik
Dasari, Ramachandra R.
Feld, Michael S.
Park, YongKeun
Yaqoob, Zahid
author_facet Hillman, Timothy R.
Yamauchi, Toyohiko
Choi, Wonshik
Dasari, Ramachandra R.
Feld, Michael S.
Park, YongKeun
Yaqoob, Zahid
author_sort Hillman, Timothy R.
collection PubMed
description Optical transmission through complex media such as biological tissue is fundamentally limited by multiple light scattering. Precise control of the optical wavefield potentially holds the key to advancing a broad range of light-based techniques and applications for imaging or optical delivery. We present a simple and robust digital optical phase conjugation (DOPC) implementation for suppressing multiple light scattering. Utilizing wavefront shaping via a spatial light modulator (SLM), we demonstrate its turbidity-suppression capability by reconstructing the image of a complex two-dimensional wide-field target through a highly scattering medium. Employing an interferometer with a Sagnac-like ring design, we successfully overcome the challenging alignment and wavefront-matching constraints in DOPC, reflecting the requirement that the forward- and reverse-propagation paths through the turbid medium be identical. By measuring the output response to digital distortion of the SLM write pattern, we validate the sub-wavelength sensitivity of the system.
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spelling pubmed-36659642013-05-29 Digital optical phase conjugation for delivering two-dimensional images through turbid media Hillman, Timothy R. Yamauchi, Toyohiko Choi, Wonshik Dasari, Ramachandra R. Feld, Michael S. Park, YongKeun Yaqoob, Zahid Sci Rep Article Optical transmission through complex media such as biological tissue is fundamentally limited by multiple light scattering. Precise control of the optical wavefield potentially holds the key to advancing a broad range of light-based techniques and applications for imaging or optical delivery. We present a simple and robust digital optical phase conjugation (DOPC) implementation for suppressing multiple light scattering. Utilizing wavefront shaping via a spatial light modulator (SLM), we demonstrate its turbidity-suppression capability by reconstructing the image of a complex two-dimensional wide-field target through a highly scattering medium. Employing an interferometer with a Sagnac-like ring design, we successfully overcome the challenging alignment and wavefront-matching constraints in DOPC, reflecting the requirement that the forward- and reverse-propagation paths through the turbid medium be identical. By measuring the output response to digital distortion of the SLM write pattern, we validate the sub-wavelength sensitivity of the system. Nature Publishing Group 2013-05-29 /pmc/articles/PMC3665964/ /pubmed/23714766 http://dx.doi.org/10.1038/srep01909 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Article
Hillman, Timothy R.
Yamauchi, Toyohiko
Choi, Wonshik
Dasari, Ramachandra R.
Feld, Michael S.
Park, YongKeun
Yaqoob, Zahid
Digital optical phase conjugation for delivering two-dimensional images through turbid media
title Digital optical phase conjugation for delivering two-dimensional images through turbid media
title_full Digital optical phase conjugation for delivering two-dimensional images through turbid media
title_fullStr Digital optical phase conjugation for delivering two-dimensional images through turbid media
title_full_unstemmed Digital optical phase conjugation for delivering two-dimensional images through turbid media
title_short Digital optical phase conjugation for delivering two-dimensional images through turbid media
title_sort digital optical phase conjugation for delivering two-dimensional images through turbid media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665964/
https://www.ncbi.nlm.nih.gov/pubmed/23714766
http://dx.doi.org/10.1038/srep01909
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