The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice

The purpose of this study was to explore how genetic deletion and pharmacological antagonism of the P2X7 receptor (P2rx7) alter mood-related behaviour, gene expression and stress reactivity in the brain. The forced swim test (FST), tail suspension test (TST) and amphetamine-induced hyperlocomotion (...

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Detalles Bibliográficos
Autores principales: Csölle, Cecilia, Andó, Rómeó D., Kittel, Ágnes, Gölöncsér, Flóra, Baranyi, Mária, Soproni, Krisztina, Zelena, Dóra, Haller, József, Németh, Tamás, Mócsai, Attila, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666310/
https://www.ncbi.nlm.nih.gov/pubmed/22243662
http://dx.doi.org/10.1017/S1461145711001933

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