Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection

RNA interference (RNAi)-based therapeutics have the potential to treat chronic hepatitis B virus (HBV) infection in a fundamentally different manner than current therapies. Using RNAi, it is possible to knock down expression of viral RNAs including the pregenomic RNA from which the replicative inter...

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Detalles Bibliográficos
Autores principales: Wooddell, Christine I, Rozema, David B, Hossbach, Markus, John, Matthias, Hamilton, Holly L, Chu, Qili, Hegge, Julia O, Klein, Jason J, Wakefield, Darren H, Oropeza, Claudia E, Deckert, Jochen, Roehl, Ingo, Jahn-Hofmann, Kerstin, Hadwiger, Philipp, Vornlocher, Hans-Peter, McLachlan, Alan, Lewis, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666629/
https://www.ncbi.nlm.nih.gov/pubmed/23439496
http://dx.doi.org/10.1038/mt.2013.31

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