A structural role for the PHP domain in E. coli DNA polymerase III

BACKGROUND: In addition to the core catalytic machinery, bacterial replicative DNA polymerases contain a Polymerase and Histidinol Phosphatase (PHP) domain whose function is not entirely understood. The PHP domains of some bacterial replicases are active metal-dependent nucleases that may play a rol...

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Detalles Bibliográficos
Autores principales: Barros, Tiago, Guenther, Joel, Kelch, Brian, Anaya, Jordan, Prabhakar, Arjun, O’Donnell, Mike, Kuriyan, John, Lamers, Meindert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666897/
https://www.ncbi.nlm.nih.gov/pubmed/23672456
http://dx.doi.org/10.1186/1472-6807-13-8

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