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Developmental patterns of DR6 in normal human hippocampus and in Down syndrome
BACKGROUND: Death receptor 6 (DR6) is highly expressed in the human brain: it has been shown to induce axon pruning and neuron death via distinct caspases and to mediate axonal degeneration through binding to N-terminal β amyloid precursor protein (N-APP). METHODS: We investigated the expression of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666921/ https://www.ncbi.nlm.nih.gov/pubmed/23618225 http://dx.doi.org/10.1186/1866-1955-5-10 |