Inhibitory effects of epigenetic modulators and differentiation inducers on human medulloblastoma cell lines

BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in childhood with a 5-year survival of approximately 60%. We have recently shown that treatment of human MB cells with 5-aza-2’-deoxycytidine (5-aza-dC) reduces the clonogenic survival significantly. Here, we tested combinator...

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Detalles Bibliográficos
Autores principales: Patties, Ina, Kortmann, Rolf-Dieter, Glasow, Annegret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666942/
https://www.ncbi.nlm.nih.gov/pubmed/23672687
http://dx.doi.org/10.1186/1756-9966-32-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666942/
https://www.ncbi.nlm.nih.gov/pubmed/23672687
http://dx.doi.org/10.1186/1756-9966-32-27

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