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Inhibitory effects of epigenetic modulators and differentiation inducers on human medulloblastoma cell lines
BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in childhood with a 5-year survival of approximately 60%. We have recently shown that treatment of human MB cells with 5-aza-2’-deoxycytidine (5-aza-dC) reduces the clonogenic survival significantly. Here, we tested combinator...
Autores principales: | Patties, Ina, Kortmann, Rolf-Dieter, Glasow, Annegret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666942/ https://www.ncbi.nlm.nih.gov/pubmed/23672687 http://dx.doi.org/10.1186/1756-9966-32-27 |
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