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Hierarchical Organization of Multi-Site Phosphorylation at the CXCR4 C Terminus

The chemokine receptor CXCR4 regulates cell migration during ontogenesis and disease states including cancer and inflammation. Upon stimulation by the endogenous ligand CXCL12, CXCR4 becomes phosphorylated at multiple sites in its C-terminal domain. Mutations in the CXCR4 gene affecting C-terminal p...

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Detalles Bibliográficos
Autores principales:	Mueller, Wiebke, Schütz, Dagmar, Nagel, Falko, Schulz, Stefan, Stumm, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666969/ https://www.ncbi.nlm.nih.gov/pubmed/23734232 http://dx.doi.org/10.1371/journal.pone.0064975

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