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Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts
BACKGROUND: Platelet-derived growth factor (PDGF) signalling is essential for many key cellular processes in mesenchymal cells. As there is redundancy in signalling between the five PDGF ligand isoforms and three PDGF receptor isoforms, and deletion of either of the receptors in vivo produces an emb...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667071/ https://www.ncbi.nlm.nih.gov/pubmed/23663505 http://dx.doi.org/10.1186/1755-1536-6-10 |