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Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish
Corticotropin-releasing hormone (CRH) is a hypothalamic neuropeptide belonging to a family of neuropeptides that includes urocortins, urotensin I, and sauvagine in vertebrates. CRH and urocortin act as anorexigenic factors for satiety regulation in fish. In a goldfish model, intracerebroventricular...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667241/ https://www.ncbi.nlm.nih.gov/pubmed/23754974 http://dx.doi.org/10.3389/fnins.2013.00091 |
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author | Matsuda, Kouhei |
author_facet | Matsuda, Kouhei |
author_sort | Matsuda, Kouhei |
collection | PubMed |
description | Corticotropin-releasing hormone (CRH) is a hypothalamic neuropeptide belonging to a family of neuropeptides that includes urocortins, urotensin I, and sauvagine in vertebrates. CRH and urocortin act as anorexigenic factors for satiety regulation in fish. In a goldfish model, intracerebroventricular (ICV) administration of CRH has been shown to affect not only food intake, but also locomotor and psychomotor activities. In particular, CRH elicits anxiety-like behavior as an anxiogenic neuropeptide in goldfish, as is the case in rodents. This paper reviews current knowledge of CRH and its related peptides derived from studies of teleost fish, as representative non-mammals, focusing particularly on the role of the CRH system, and examines its significance from a comparative viewpoint. |
format | Online Article Text |
id | pubmed-3667241 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-36672412013-06-10 Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish Matsuda, Kouhei Front Neurosci Endocrinology Corticotropin-releasing hormone (CRH) is a hypothalamic neuropeptide belonging to a family of neuropeptides that includes urocortins, urotensin I, and sauvagine in vertebrates. CRH and urocortin act as anorexigenic factors for satiety regulation in fish. In a goldfish model, intracerebroventricular (ICV) administration of CRH has been shown to affect not only food intake, but also locomotor and psychomotor activities. In particular, CRH elicits anxiety-like behavior as an anxiogenic neuropeptide in goldfish, as is the case in rodents. This paper reviews current knowledge of CRH and its related peptides derived from studies of teleost fish, as representative non-mammals, focusing particularly on the role of the CRH system, and examines its significance from a comparative viewpoint. Frontiers Media S.A. 2013-05-30 /pmc/articles/PMC3667241/ /pubmed/23754974 http://dx.doi.org/10.3389/fnins.2013.00091 Text en Copyright © 2013 Matsuda. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Endocrinology Matsuda, Kouhei Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title | Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title_full | Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title_fullStr | Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title_full_unstemmed | Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title_short | Regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (CRH) in fish |
title_sort | regulation of feeding behavior and psychomotor activity by corticotropin-releasing hormone (crh) in fish |
topic | Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667241/ https://www.ncbi.nlm.nih.gov/pubmed/23754974 http://dx.doi.org/10.3389/fnins.2013.00091 |
work_keys_str_mv | AT matsudakouhei regulationoffeedingbehaviorandpsychomotoractivitybycorticotropinreleasinghormonecrhinfish |