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Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes

Botanicals constitute a large part of the drugs from the traditional medicine (TM) and ethno medicine (EM) known for their history of safe use (HOSU). Phytopharmaceuticals having a base of such origin offer high advantages as they come with safety profiles, and often allow extrapolation of the HOSU...

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Autor principal: Anantha, Narayana D. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667432/
https://www.ncbi.nlm.nih.gov/pubmed/23741154
http://dx.doi.org/10.4103/0975-9476.109542
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author Anantha, Narayana D. B.
author_facet Anantha, Narayana D. B.
author_sort Anantha, Narayana D. B.
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description Botanicals constitute a large part of the drugs from the traditional medicine (TM) and ethno medicine (EM) known for their history of safe use (HOSU). Phytopharmaceuticals having a base of such origin offer high advantages as they come with safety profiles, and often allow extrapolation of the HOSU data, under certain circumstances. However, while current pharmaceutical technologies are being adopted by the industry to make phytopharmaceuticals with such origin, there is a need for preformulation research and development (R and D) during formulation. Some suggestions for R and D studies in case of aqueous extracts known in Ayurveda, converted on an industrial scale to obtain a phytopharmaceutical, and formulated as a solid dosage form (granules, tablets, or capsules) are discussed.
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spelling pubmed-36674322013-06-05 Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes Anantha, Narayana D. B. J Ayurveda Integr Med Thought Leadership Article Botanicals constitute a large part of the drugs from the traditional medicine (TM) and ethno medicine (EM) known for their history of safe use (HOSU). Phytopharmaceuticals having a base of such origin offer high advantages as they come with safety profiles, and often allow extrapolation of the HOSU data, under certain circumstances. However, while current pharmaceutical technologies are being adopted by the industry to make phytopharmaceuticals with such origin, there is a need for preformulation research and development (R and D) during formulation. Some suggestions for R and D studies in case of aqueous extracts known in Ayurveda, converted on an industrial scale to obtain a phytopharmaceutical, and formulated as a solid dosage form (granules, tablets, or capsules) are discussed. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3667432/ /pubmed/23741154 http://dx.doi.org/10.4103/0975-9476.109542 Text en Copyright: © Journal of Ayurveda and Integrative Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Thought Leadership Article
Anantha, Narayana D. B.
Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title_full Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title_fullStr Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title_full_unstemmed Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title_short Approaches to pre-formulation R and D for phytopharmaceuticals emanating from herb based traditional Ayurvedic processes
title_sort approaches to pre-formulation r and d for phytopharmaceuticals emanating from herb based traditional ayurvedic processes
topic Thought Leadership Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667432/
https://www.ncbi.nlm.nih.gov/pubmed/23741154
http://dx.doi.org/10.4103/0975-9476.109542
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