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Post-injury protective astrogenesis from SVZ niche is controlled by Notch modulator Thbs4

Postnatal/adult neural stem cells (NSCs) within the rodent subventricular/subependymal zone (SVZ/SEZ) generate Doublecortin (DCX)(+) neuroblasts that migrate and integrate into olfactory bulb circuitry(1,2). Continuous production of neuroblasts is controlled by SVZ microenvironmental niche(3,4). It...

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Detalles Bibliográficos
Autores principales: Benner, Eric J., Luciano, Dominic, Jo, Rebecca, Abdi, Khadar, Paez-Gonzalez, Patricia, Sheng, Huaxin, Warner, David, Liu, Chunlei, Eroglu, Cagla, Kuo, Chay T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667629/
https://www.ncbi.nlm.nih.gov/pubmed/23615612
http://dx.doi.org/10.1038/nature12069