Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: expression of elevated levels of a cholinergic-specific ganglioside, GT1aα

In order to examine the potential involvement of gangliosides in AD (Alzheimer's disease), we compared the ganglioside compositions of the brains of a double-transgenic (Tg) mouse model [APP (amyloid precursor protein)/PSEN1 (presenilin)] of AD and a triple mutant mouse model with an additional...

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Detalles Bibliográficos
Autores principales: Ariga, Toshio, Itokazu, Yutaka, McDonald, Michael P., Hirabayashi, Yoshio, Ando, Susumu, Yu, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667643/
https://www.ncbi.nlm.nih.gov/pubmed/23565921
http://dx.doi.org/10.1042/AN20130006

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