Mutation of SIMPLE in Charcot–Marie–Tooth 1C alters production of exosomes

Charcot–Marie–Tooth (CMT) disease is an inherited neurological disorder. Mutations in the small integral membrane protein of the lysosome/late endosome (SIMPLE) account for the rare autosomal-dominant demyelination in CMT1C patients. Understanding the molecular basis of CMT1C pathogenesis is impeded...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Hong, Guariglia, Sara, Yu, Raymond Y. L., Li, Wenjing, Brancho, Deborah, Peinado, Hector, Lyden, David, Salzer, James, Bennett, Craig, Chow, Chi-Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667717/
https://www.ncbi.nlm.nih.gov/pubmed/23576546
http://dx.doi.org/10.1091/mbc.E12-07-0544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667717/
https://www.ncbi.nlm.nih.gov/pubmed/23576546
http://dx.doi.org/10.1091/mbc.E12-07-0544

Ejemplares similares