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Dual effects of Ral-activated pathways on p27 localization and TGF-β signaling

Constitutive activation or overactivation of Ras signaling pathways contributes to epithelial tumorigenesis in several ways, one of which is cytoplasmic mislocalization of the cyclin-dependent kinase inhibitor p27(Kip1) (p27). We previously showed that such an effect can be mediated by activation of...

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Detalles Bibliográficos
Autores principales:	Tazat, Keren, Harsat, Meirav, Goldshmid-Shagal, Ayelet, Ehrlich, Marcelo, Henis, Yoav I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667732/ https://www.ncbi.nlm.nih.gov/pubmed/23576547 http://dx.doi.org/10.1091/mbc.E13-01-0007

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