Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay

HIV-1 persists in infected individuals in a stable pool of resting CD4(+) T cells as a latent but replication-competent provirus. This latent reservoir is the major barrier to the eradication of HIV-1. Clinical trials are currently underway investigating the effects of latency-disrupting compounds o...

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Detalles Bibliográficos
Autores principales: Laird, Gregory M., Eisele, Evelyn E., Rabi, S. Alireza, Lai, Jun, Chioma, Stanley, Blankson, Joel N., Siliciano, Janet D., Siliciano, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667757/
https://www.ncbi.nlm.nih.gov/pubmed/23737751
http://dx.doi.org/10.1371/journal.ppat.1003398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667757/
https://www.ncbi.nlm.nih.gov/pubmed/23737751
http://dx.doi.org/10.1371/journal.ppat.1003398

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