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CNF1 Increases Brain Energy Level, Counteracts Neuroinflammatory Markers and Rescues Cognitive Deficits in a Murine Model of Alzheimer's Disease

Overexpression of pro-inflammatory cytokines and cellular energy failure are associated with neuroinflammatory disorders, such as Alzheimer's disease. Transgenic mice homozygous for human ApoE4 gene, a well known AD and atherosclerosis animal model, show decreased levels of ATP, increased infla...

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Detalles Bibliográficos
Autores principales:	Loizzo, Stefano, Rimondini, Roberto, Travaglione, Sara, Fabbri, Alessia, Guidotti, Marco, Ferri, Alberto, Campana, Gabriele, Fiorentini, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667817/ https://www.ncbi.nlm.nih.gov/pubmed/23738020 http://dx.doi.org/10.1371/journal.pone.0065898

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