Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression

Inappropriate surface expression of voltage-gated Ca(2+)channels (Ca(V)) in pancreatic ß-cells may contribute to the development of type 2 diabetes. First, failure to increase intracellular Ca(2+) concentrations at the sites of exocytosis impedes insulin release. Furthermore, excessive Ca(2+) influx...

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Detalles Bibliográficos
Autores principales: Buda, Pawel, Reinbothe, Thomas, Nagaraj, Vini, Mahdi, Taman, Luan, Cheng, Tang, Yunzhao, Axelsson, Annika S., Li, Daiqing, Rosengren, Anders H., Renström, Erik, Zhang, Enming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667822/
https://www.ncbi.nlm.nih.gov/pubmed/23737983
http://dx.doi.org/10.1371/journal.pone.0064462

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