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16 kDa Heat Shock Protein from Heat-Inactivated Mycobacterium tuberculosis Is a Homodimer – Suitability for Diagnostic Applications with Specific Llama VHH Monoclonals

BACKGROUND: The 16 kDa heat shock protein (HSP) is an immuno-dominant antigen, used in diagnosis of infectious Mycobacterium tuberculosis (M.tb.) causing tuberculosis (TB). Its use in serum-based diagnostics is limited, but for the direct identification of M.tb. bacteria in sputum or cultures it may...

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Detalles Bibliográficos
Autores principales:	Srivastava, Saurabh K., Ruigrok, Vincent J. B., Thompson, Natalie J., Trilling, Anke K., Heck, Albert J. R., van Rijn, Cees, Beekwilder, Jules, Jongsma, Maarten A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667823/ https://www.ncbi.nlm.nih.gov/pubmed/23737964 http://dx.doi.org/10.1371/journal.pone.0064040

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