Mechanistic Model of Rothia mucilaginosa Adaptation toward Persistence in the CF Lung, Based on a Genome Reconstructed from Metagenomic Data

The impaired mucociliary clearance in individuals with Cystic Fibrosis (CF) enables opportunistic pathogens to colonize CF lungs. Here we show that Rothia mucilaginosa is a common CF opportunist that was present in 83% of our patient cohort, almost as prevalent as Pseudomonas aeruginosa (89%). Seque...

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Detalles Bibliográficos
Autores principales: Lim, Yan Wei, Schmieder, Robert, Haynes, Matthew, Furlan, Mike, Matthews, T. David, Whiteson, Katrine, Poole, Stephen J., Hayes, Christopher S., Low, David A., Maughan, Heather, Edwards, Robert, Conrad, Douglas, Rohwer, Forest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667864/
https://www.ncbi.nlm.nih.gov/pubmed/23737977
http://dx.doi.org/10.1371/journal.pone.0064285

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