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The two faces of regulatory T cells in cancer

Regulatory T cells (Tregs) that expand in human colon cancer express retinoid-related orphan receptor γt (RORγt) and exert potent T-cell suppressive functions while mediating pro-inflammatory effects. Similar Tregs expand and drive a vicious cycle of inflammation in murine polyposis. Targeting RORγt...

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Detalles Bibliográficos
Autores principales:	Blatner, Nichole R, Gounari, Fotini, Khazaie, Khashayarsha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667893/ https://www.ncbi.nlm.nih.gov/pubmed/23762787 http://dx.doi.org/10.4161/onci.23852

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