Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis

Breast tumors infiltrated by matrix metalloprotease 11 (MMP-11)(+) mononuclear inflammatory cells are prone to form metastases; express high levels of interleukin (IL)-1, IL-5, IL-6, IL-17, interferon β (IFNβ) and NFκB; and exhibit an increased CD68(+)/(CD3(+)CD20(+)) cell ratio at their invasive fr...

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Detalles Bibliográficos
Autores principales: Eiró, Noemi, Fernandez-Garcia, Belen, González, Luis O., Vizoso, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667897/
https://www.ncbi.nlm.nih.gov/pubmed/23762791
http://dx.doi.org/10.4161/onci.24010
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author Eiró, Noemi
Fernandez-Garcia, Belen
González, Luis O.
Vizoso, Francisco J.
author_facet Eiró, Noemi
Fernandez-Garcia, Belen
González, Luis O.
Vizoso, Francisco J.
author_sort Eiró, Noemi
collection PubMed
description Breast tumors infiltrated by matrix metalloprotease 11 (MMP-11)(+) mononuclear inflammatory cells are prone to form metastases; express high levels of interleukin (IL)-1, IL-5, IL-6, IL-17, interferon β (IFNβ) and NFκB; and exhibit an increased CD68(+)/(CD3(+)CD20(+)) cell ratio at their invasive front. These factors, which are implicated in the crosstalk between tumors and their inflammatory microenvironment, may emerge as attractive prognostic factors and therapeutic targets.
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spelling pubmed-36678972013-06-12 Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis Eiró, Noemi Fernandez-Garcia, Belen González, Luis O. Vizoso, Francisco J. Oncoimmunology Author's View Breast tumors infiltrated by matrix metalloprotease 11 (MMP-11)(+) mononuclear inflammatory cells are prone to form metastases; express high levels of interleukin (IL)-1, IL-5, IL-6, IL-17, interferon β (IFNβ) and NFκB; and exhibit an increased CD68(+)/(CD3(+)CD20(+)) cell ratio at their invasive front. These factors, which are implicated in the crosstalk between tumors and their inflammatory microenvironment, may emerge as attractive prognostic factors and therapeutic targets. Landes Bioscience 2013-05-01 2013-05-01 /pmc/articles/PMC3667897/ /pubmed/23762791 http://dx.doi.org/10.4161/onci.24010 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Eiró, Noemi
Fernandez-Garcia, Belen
González, Luis O.
Vizoso, Francisco J.
Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title_full Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title_fullStr Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title_full_unstemmed Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title_short Cytokines related to MMP-11 expression by inflammatory cells and breast cancer metastasis
title_sort cytokines related to mmp-11 expression by inflammatory cells and breast cancer metastasis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667897/
https://www.ncbi.nlm.nih.gov/pubmed/23762791
http://dx.doi.org/10.4161/onci.24010
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AT gonzalezluiso cytokinesrelatedtommp11expressionbyinflammatorycellsandbreastcancermetastasis
AT vizosofranciscoj cytokinesrelatedtommp11expressionbyinflammatorycellsandbreastcancermetastasis

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