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The myeloid response to pancreatic carcinogenesis is regulated by the receptor for advanced glycation end-products
We identified a critical role for receptor for advanced glycation end products (RAGE) in the intratumoral accumulation of myeloid-derived suppressor cells (MDSCs) during pancreatic carcinogenesis. The absence of RAGE markedly delayed neoplasia and limited MDSC accumulation in mice expressing an onco...
Autores principales: | Vernon, Philip J., Zeh III, Herbert J., Lotze, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667906/ https://www.ncbi.nlm.nih.gov/pubmed/23762800 http://dx.doi.org/10.4161/onci.24184 |
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