Balance is a key for happiness

Eliminating one immunosuppressive mechanism is rarely sufficient to overcome cancer. One of reasons underlying this fact is that whether regulatory T cells (Tregs) or type II natural killer T (NKT) cells dominate immunosuppression depends on the mutual interactions between the latter and their type...

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Detalles Bibliográficos
Autores principales: Izhak, Liat, Berzofsky, Jay A., Terabe, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667907/
https://www.ncbi.nlm.nih.gov/pubmed/23762801
http://dx.doi.org/10.4161/onci.24211
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author Izhak, Liat
Berzofsky, Jay A.
Terabe, Masaki
author_facet Izhak, Liat
Berzofsky, Jay A.
Terabe, Masaki
author_sort Izhak, Liat
collection PubMed
description Eliminating one immunosuppressive mechanism is rarely sufficient to overcome cancer. One of reasons underlying this fact is that whether regulatory T cells (Tregs) or type II natural killer T (NKT) cells dominate immunosuppression depends on the mutual interactions between the latter and their type I counterparts. Thus, the balance among three immunomodulatory cell types dictates whether eliminating Tregs relieves or not immunosuppression.
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spelling pubmed-36679072013-06-12 Balance is a key for happiness Izhak, Liat Berzofsky, Jay A. Terabe, Masaki Oncoimmunology Author's View Eliminating one immunosuppressive mechanism is rarely sufficient to overcome cancer. One of reasons underlying this fact is that whether regulatory T cells (Tregs) or type II natural killer T (NKT) cells dominate immunosuppression depends on the mutual interactions between the latter and their type I counterparts. Thus, the balance among three immunomodulatory cell types dictates whether eliminating Tregs relieves or not immunosuppression. Landes Bioscience 2013-05-01 2013-05-01 /pmc/articles/PMC3667907/ /pubmed/23762801 http://dx.doi.org/10.4161/onci.24211 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Izhak, Liat
Berzofsky, Jay A.
Terabe, Masaki
Balance is a key for happiness
title Balance is a key for happiness
title_full Balance is a key for happiness
title_fullStr Balance is a key for happiness
title_full_unstemmed Balance is a key for happiness
title_short Balance is a key for happiness
title_sort balance is a key for happiness
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667907/
https://www.ncbi.nlm.nih.gov/pubmed/23762801
http://dx.doi.org/10.4161/onci.24211
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