Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells

Attenuated measles viruses (MV) are assessed in clinical trials for their capacity to preferentially infect and kill tumor cells. We recently showed that MV-infected tumor cells are able to activate tumor antigen cross-presentation by myeloid and plasmacytoid dendritic cells. Thus, MV-based antitumo...

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Autores principales: Fonteneau, Jean-François, Guillerme, Jean-Baptiste, Tangy, Frédéric, Grégoire, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667908/
https://www.ncbi.nlm.nih.gov/pubmed/23762802
http://dx.doi.org/10.4161/onci.24212
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author Fonteneau, Jean-François
Guillerme, Jean-Baptiste
Tangy, Frédéric
Grégoire, Marc
author_facet Fonteneau, Jean-François
Guillerme, Jean-Baptiste
Tangy, Frédéric
Grégoire, Marc
author_sort Fonteneau, Jean-François
collection PubMed
description Attenuated measles viruses (MV) are assessed in clinical trials for their capacity to preferentially infect and kill tumor cells. We recently showed that MV-infected tumor cells are able to activate tumor antigen cross-presentation by myeloid and plasmacytoid dendritic cells. Thus, MV-based antitumor virotherapy may stimulate antitumor immune response.
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spelling pubmed-36679082013-06-12 Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells Fonteneau, Jean-François Guillerme, Jean-Baptiste Tangy, Frédéric Grégoire, Marc Oncoimmunology Author's View Attenuated measles viruses (MV) are assessed in clinical trials for their capacity to preferentially infect and kill tumor cells. We recently showed that MV-infected tumor cells are able to activate tumor antigen cross-presentation by myeloid and plasmacytoid dendritic cells. Thus, MV-based antitumor virotherapy may stimulate antitumor immune response. Landes Bioscience 2013-05-01 2013-05-01 /pmc/articles/PMC3667908/ /pubmed/23762802 http://dx.doi.org/10.4161/onci.24212 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Fonteneau, Jean-François
Guillerme, Jean-Baptiste
Tangy, Frédéric
Grégoire, Marc
Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title_full Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title_fullStr Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title_full_unstemmed Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title_short Attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
title_sort attenuated measles virus used as an oncolytic virus activates myeloid and plasmacytoid dendritic cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667908/
https://www.ncbi.nlm.nih.gov/pubmed/23762802
http://dx.doi.org/10.4161/onci.24212
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