Cargando…
A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China
BACKGROUND: Insecticide resistance in malaria vectors is a growing concern in many countries and requires immediate attention because of the limited chemical arsenal available for vector control. There is lack of systematic and standard monitoring data of malaria vector resistance in the endemic are...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668211/ https://www.ncbi.nlm.nih.gov/pubmed/23683359 http://dx.doi.org/10.1186/1475-2875-12-164 |
_version_ | 1782271592259125248 |
---|---|
author | Wang, Duo-quan Xia, Zhi-gui Zhou, Shui-sen Zhou, Xiao-nong Wang, Ru-bo Zhang, Qing-feng |
author_facet | Wang, Duo-quan Xia, Zhi-gui Zhou, Shui-sen Zhou, Xiao-nong Wang, Ru-bo Zhang, Qing-feng |
author_sort | Wang, Duo-quan |
collection | PubMed |
description | BACKGROUND: Insecticide resistance in malaria vectors is a growing concern in many countries and requires immediate attention because of the limited chemical arsenal available for vector control. There is lack of systematic and standard monitoring data of malaria vector resistance in the endemic areas, which is essential for the ambitious goal of malaria elimination programme of China. METHODS: In 2010, eight provinces from different malaria endemic region were selected for study areas. Bioassays were performed on F1 progeny of Anopheles sinensis reared from wild-caught females using the standard WHO susceptibility test with diagnostic concentrations of 0.25% deltamethrin and 4% DDT. RESULTS: For An. sinensis, the results indicated that exposure to 0.25% deltamethrin of F1 families with mortalities ranging from 5.96% to 64.54% and less than 80% mortality to DDT at the diagnostic concentration of 4% across the study areas. CONCLUSIONS: Anopheles sinensis was completely resistant to both deltamethrin and DDT, and resistance to pyrethroid has risen strikingly compared to that recorded during 1990s. The results highlight the importance of longitudinal insecticide resistance monitoring and the urgent need for a better understanding of the status of insecticide resistance in this region. |
format | Online Article Text |
id | pubmed-3668211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-36682112013-06-01 A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China Wang, Duo-quan Xia, Zhi-gui Zhou, Shui-sen Zhou, Xiao-nong Wang, Ru-bo Zhang, Qing-feng Malar J Research BACKGROUND: Insecticide resistance in malaria vectors is a growing concern in many countries and requires immediate attention because of the limited chemical arsenal available for vector control. There is lack of systematic and standard monitoring data of malaria vector resistance in the endemic areas, which is essential for the ambitious goal of malaria elimination programme of China. METHODS: In 2010, eight provinces from different malaria endemic region were selected for study areas. Bioassays were performed on F1 progeny of Anopheles sinensis reared from wild-caught females using the standard WHO susceptibility test with diagnostic concentrations of 0.25% deltamethrin and 4% DDT. RESULTS: For An. sinensis, the results indicated that exposure to 0.25% deltamethrin of F1 families with mortalities ranging from 5.96% to 64.54% and less than 80% mortality to DDT at the diagnostic concentration of 4% across the study areas. CONCLUSIONS: Anopheles sinensis was completely resistant to both deltamethrin and DDT, and resistance to pyrethroid has risen strikingly compared to that recorded during 1990s. The results highlight the importance of longitudinal insecticide resistance monitoring and the urgent need for a better understanding of the status of insecticide resistance in this region. BioMed Central 2013-05-17 /pmc/articles/PMC3668211/ /pubmed/23683359 http://dx.doi.org/10.1186/1475-2875-12-164 Text en Copyright © 2013 Wang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Wang, Duo-quan Xia, Zhi-gui Zhou, Shui-sen Zhou, Xiao-nong Wang, Ru-bo Zhang, Qing-feng A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title | A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title_full | A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title_fullStr | A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title_full_unstemmed | A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title_short | A potential threat to malaria elimination: extensive deltamethrin and DDT resistance to Anopheles sinensis from the malaria-endemic areas in China |
title_sort | potential threat to malaria elimination: extensive deltamethrin and ddt resistance to anopheles sinensis from the malaria-endemic areas in china |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668211/ https://www.ncbi.nlm.nih.gov/pubmed/23683359 http://dx.doi.org/10.1186/1475-2875-12-164 |
work_keys_str_mv | AT wangduoquan apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT xiazhigui apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhoushuisen apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhouxiaonong apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT wangrubo apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhangqingfeng apotentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT wangduoquan potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT xiazhigui potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhoushuisen potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhouxiaonong potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT wangrubo potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina AT zhangqingfeng potentialthreattomalariaeliminationextensivedeltamethrinandddtresistancetoanophelessinensisfromthemalariaendemicareasinchina |