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Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lipid dysregulation is suggested to participate in AD pathogenesis. However, alter...

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Detalles Bibliográficos
Autores principales:	Tajima, Yoko, Ishikawa, Masaki, Maekawa, Keiko, Murayama, Mayumi, Senoo, Yuya, Nishimaki-Mogami, Tomoko, Nakanishi, Hiroki, Ikeda, Kazutaka, Arita, Makoto, Taguchi, Ryo, Okuno, Alato, Mikawa, Ryuta, Niida, Shumpei, Takikawa, Osamu, Saito, Yoshiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668217/ https://www.ncbi.nlm.nih.gov/pubmed/23659495 http://dx.doi.org/10.1186/1476-511X-12-68

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