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In vivo effect of statins on the expression of the HIV co-receptors CCR5 and CXCR4

BACKGROUND: During the HIV-1 replication cycle, several molecules including chemokine receptors and cholesterol are crucial, and are therefore potential targets for therapeutic intervention. Indeed statins, compounds that inhibit cellular synthesis of cholesterol and have anti-inflammatory and immun...

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Detalles Bibliográficos
Autores principales:	Higuita, Edwin A, Jaimes, Fabián A, Rugeles, Maria T, Montoya, Carlos J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668251/ https://www.ncbi.nlm.nih.gov/pubmed/23634877 http://dx.doi.org/10.1186/1742-6405-10-10

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