The role of microRNAs in the pathogenesis of MMPi-induced skin fibrodysplasia

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes involved in extracellular matrix (ECM) homeostasis. MMPs have been an attractive pharmacological target for a number of indications. However, development has been hampered by the propensity of compounds targeting these...

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Detalles Bibliográficos
Autores principales: Tonge, Daniel P, Tugwood, Jonathan D, Kelsall, Janet, Gant, Timothy W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668254/
https://www.ncbi.nlm.nih.gov/pubmed/23688202
http://dx.doi.org/10.1186/1471-2164-14-338

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