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Computational modelling of the regulation of Insulin signalling by oxidative stress

BACKGROUND: Existing models of insulin signalling focus on short term dynamics, rather than the longer term dynamics necessary to understand many physiologically relevant behaviours. We have developed a model of insulin signalling in rodent adipocytes that includes both transcriptional feedback thro...

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Detalles Bibliográficos
Autores principales: Smith, Graham R, Shanley, Daryl P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668293/
https://www.ncbi.nlm.nih.gov/pubmed/23705851
http://dx.doi.org/10.1186/1752-0509-7-41