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A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity
Histone modifications are now well-established mediators of transcriptional programs that distinguish cell states. However, the kinetics of histone modification and their role in mediating rapid, signal-responsive gene expression changes has been little studied on a genome-wide scale. Vascular endot...
Autores principales: | Zhang, Bing, Day, Daniel S., Ho, Joshua W., Song, Lingyun, Cao, Jingjing, Christodoulou, Danos, Seidman, Jonathan G., Crawford, Gregory E., Park, Peter J., Pu, William T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668360/ https://www.ncbi.nlm.nih.gov/pubmed/23547170 http://dx.doi.org/10.1101/gr.149674.112 |
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