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A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation
BACKGROUND: Ex vivo colospheres have been previously characterised as a colorectal cancer (CRC) well-rounded multicellular model, exclusively formed by carcinoma cells, and derived from fresh CRC tissue after mechanical dissociation. The ability to form colospheres was correlated with tumour aggress...
Autores principales: | Weiswald, L-B, Richon, S, Massonnet, G, Guinebretière, J-M, Vacher, S, Laurendeau, I, Cottu, P, Marangoni, E, Nemati, F, Validire, P, Bellet, D, Bièche, I, Dangles-Marie, V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668460/ https://www.ncbi.nlm.nih.gov/pubmed/23538387 http://dx.doi.org/10.1038/bjc.2013.132 |
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