DNA copy number profiling reveals extensive genomic loss in hereditary BRCA1 and BRCA2 ovarian carcinomas

BACKGROUND: Few studies have attempted to characterise genomic changes occurring in hereditary epithelial ovarian carcinomas (EOCs) and inconsistent results have been obtained. Given the relevance of DNA copy number alterations in ovarian oncogenesis and growing clinical implications of the BRCA-gen...

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Detalles Bibliográficos
Autores principales: Kamieniak, M M, Muñoz-Repeto, I, Rico, D, Osorio, A, Urioste, M, García-Donas, J, Hernando, S, Robles-Díaz, L, Ramón y Cajal, T, Cazorla, A, Sáez, R, García-Bueno, J M, Domingo, S, Borrego, S, Palacios, J, van de Wiel, M A, Ylstra, B, Benítez, J, García, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668473/
https://www.ncbi.nlm.nih.gov/pubmed/23558894
http://dx.doi.org/10.1038/bjc.2013.141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668473/
https://www.ncbi.nlm.nih.gov/pubmed/23558894
http://dx.doi.org/10.1038/bjc.2013.141

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