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Trolox contributes to Nrf2-mediated protection of human and murine primary alveolar type II cells from injury by cigarette smoke

Cigarette smoke (CS) is a main risk factor for chronic obstructive pulmonary disease (COPD). Oxidative stress induced by CS causes DNA and lung damage. Oxidant/antioxidant imbalance occurs in the distal air spaces of smokers and in patients with COPD. We studied the effect of oxidative stress genera...

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Detalles Bibliográficos
Autores principales:	Messier, E M, Bahmed, K, Tuder, R M, Chu, H W, Bowler, R P, Kosmider, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668634/ https://www.ncbi.nlm.nih.gov/pubmed/23559007 http://dx.doi.org/10.1038/cddis.2013.96

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