Calcium-activated and apoptotic phospholipid scrambling induced by Ano6 can occur independently of Ano6 ion currents

Immune cells and platelets maintain plasma membrane phospholipid asymmetry. Upon activation, this asymmetry is disrupted by phospholipid scrambling (PS), which is a major step during activation of immune cells, hemostasis and apoptosis. Anoctamin 6 (Ano6; TMEM16F) causes chloride (Cl(−)) and cation...

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Detalles Bibliográficos
Autores principales: Kmit, A, van Kruchten, R, Ousingsawat, J, Mattheij, N J A, Senden-Gijsbers, B, Heemskerk, J W M, Schreiber, R, Bevers, E M, Kunzelmann, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668637/
https://www.ncbi.nlm.nih.gov/pubmed/23618909
http://dx.doi.org/10.1038/cddis.2013.135

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