Assembly of the Yeast Exoribonuclease Rrp6 with Its Associated Cofactor Rrp47 Occurs in the Nucleus and Is Critical for the Controlled Expression of Rrp47

Rrp6 is a key catalytic subunit of the nuclear RNA exosome that plays a pivotal role in the processing, degradation, and quality control of a wide range of cellular RNAs. Here we report our findings on the assembly of the complex involving Rrp6 and its associated protein Rrp47, which is required for...

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Detalles Bibliográficos
Autores principales: Feigenbutz, Monika, Jones, Rebecca, Besong, Tabot M. D., Harding, Stephen E., Mitchell, Phil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668751/
https://www.ncbi.nlm.nih.gov/pubmed/23580640
http://dx.doi.org/10.1074/jbc.M112.445759

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