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Development of biodegradable methylprednisolone microparticles for treatment of articular pathology using a spray-drying technique
In this work, microparticles were prepared by spray-drying using albumin, chondroitin sulfate, and hyaluronic acid as excipients to create a controlled-release methylprednisolone system for use in inflammatory disorders such as arthritis. Scanning electron microscopy demonstrated that these micropar...
Autores principales: | Tobar-Grande, Blanca, Godoy, Ricardo, Bustos, Paulina, von Plessing, Carlos, Fattal, Elias, Tsapis, Nicolas, Olave, Claudia, Gómez-Gaete, Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668958/ https://www.ncbi.nlm.nih.gov/pubmed/23737670 http://dx.doi.org/10.2147/IJN.S39327 |
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