Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China

BACKGROUND: The role of tumor suppressor gene RASSF1A in the esophageal and gastric cardia carcinogenesis is still inconclusive. In this study, the polymorphism, promoter methylation and gene expression of RASSF1A were characterized in esophageal squamous cell carcinoma (ESCC) and gastric cardia ade...

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Detalles Bibliográficos
Autores principales: Zhou, Sheng Li, Cui, Juan, Fan, Zong Min, Li, Xue Min, Li, Ji Lin, Liu, Bao Chi, Zhang, Dong Yun, Liu, Hong Yan, Zhao, Xue Ke, Song, Xin, Wang, Ran, Yan, Ze Chen, Yi, Hui Xing, Wang, Li Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668992/
https://www.ncbi.nlm.nih.gov/pubmed/23705663
http://dx.doi.org/10.1186/1471-2407-13-259

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