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The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case–control studies

BACKGROUND: The multidrug resistance (MDR) 1 gene encodes a 170-kDa membrane transporter called P-glycoprotein, which plays an important role in protecting cells against lipophilic xenobiotics by the way of an ATP-dependent cellular efflux mechanism. Three polymorphisms of MDR1, 3435C > T located...

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Detalles Bibliográficos
Autores principales:	Wang, Ling-Hui, Song, Yan-Bin, Zheng, Wen-Ling, Jiang, Ling, Ma, Wen-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669001/ https://www.ncbi.nlm.nih.gov/pubmed/23687985 http://dx.doi.org/10.1186/1475-2867-13-46

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