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Impact of pyrrolidine-bispyrrole DNA minor groove binding agents and chirality on global proteomic profile in Escherichia Coli

BACKGROUND: There is great interest in the design of small molecules that selectively target minor grooves of duplex DNA for controlling specific gene expression implicated in a disease. The design of chiral small molecules for rational drug design has attracted increasing attention due to the chira...

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Detalles Bibliográficos
Autores principales:	Yang, Ya-ting, Lin, Chun-Yu, Jeng, Jingyueh, Ong, Chi-Wi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669006/ https://www.ncbi.nlm.nih.gov/pubmed/23702249 http://dx.doi.org/10.1186/1477-5956-11-23

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