Cargando…
Brain-Derived Neurotrophic Factor-Dependent cdk1 Inhibition Prevents G2/M Progression in Differentiating Tetraploid Neurons
Neurodegeneration is often associated with DNA synthesis in neurons, the latter usually remaining for a long time as tetraploid cells before dying by apoptosis. The molecular mechanism preventing G2/M transition in these neurons remains unknown, but it may be reminiscent of the mechanism that mainta...
Autores principales: | Ovejero-Benito, María C., Frade, José M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669015/ https://www.ncbi.nlm.nih.gov/pubmed/23741412 http://dx.doi.org/10.1371/journal.pone.0064890 |
Ejemplares similares
-
Neuronal cell cycle: the neuron itself and its circumstances
por: Frade, José M, et al.
Publicado: (2015) -
p27(Kip1) participates in the regulation of endoreplication in differentiating chick retinal ganglion cells
por: Ovejero-Benito, María C, et al.
Publicado: (2015) -
Brain-Derived Neurotrophic Factor Is Involved in Activity-Dependent Tonotopic Refinement of MNTB Neurons
por: Wollet, Mackenna, et al.
Publicado: (2022) -
p53 Dependent Centrosome Clustering Prevents Multipolar Mitosis in Tetraploid Cells
por: Yi, Qiyi, et al.
Publicado: (2011) -
Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons
por: Nilbratt, Mats, et al.
Publicado: (2010)