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Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration
In neurons, mitochondria are enriched to provide energy and calcium buffering required for synaptic transmission. Additionally, mitochondria localize to the synapse, where they are critical for the mobilization of reserve pool vesicles and for neurotransmitter release. Previously, functional defects...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669018/ https://www.ncbi.nlm.nih.gov/pubmed/23711354 http://dx.doi.org/10.1186/2047-9158-2-12 |