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Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery

BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during survei...

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Autores principales: Sugimoto, Koichi, Shimizu, Nobutaka, Oki, Takashi, Nose, Kazuhiro, Nishioka, Tsukasa, Adomi, Shogo, Ohzeki, Takayuki, Esa, Atsunobu, Uemura, Hirotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669092/
https://www.ncbi.nlm.nih.gov/pubmed/23737676
http://dx.doi.org/10.2147/CMAR.S44221
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author Sugimoto, Koichi
Shimizu, Nobutaka
Oki, Takashi
Nose, Kazuhiro
Nishioka, Tsukasa
Adomi, Shogo
Ohzeki, Takayuki
Esa, Atsunobu
Uemura, Hirotsugu
author_facet Sugimoto, Koichi
Shimizu, Nobutaka
Oki, Takashi
Nose, Kazuhiro
Nishioka, Tsukasa
Adomi, Shogo
Ohzeki, Takayuki
Esa, Atsunobu
Uemura, Hirotsugu
author_sort Sugimoto, Koichi
collection PubMed
description BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during surveillance from January 2000 to December 2011. Radiographic evaluations using computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed at least every 6 months, and the tumor size was determined at least twice. RESULTS: The mean follow-up time was 26.6 ± 18.6 months and mean tumor doubling time was 23.4 ± 16.0 months. Histopathological analysis revealed that 32 of the 34 patients were malignant in pT1aN0M0. Only one patient showed tumor recurrence, who subsequently died due to tumor progression. CONCLUSION: The growth rate of the small renal mass was slow in the majority of our patients. Delayed intervention does not have a detrimental effect on cancer-specific outcomes.
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spelling pubmed-36690922013-06-04 Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery Sugimoto, Koichi Shimizu, Nobutaka Oki, Takashi Nose, Kazuhiro Nishioka, Tsukasa Adomi, Shogo Ohzeki, Takayuki Esa, Atsunobu Uemura, Hirotsugu Cancer Manag Res Original Research BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during surveillance from January 2000 to December 2011. Radiographic evaluations using computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed at least every 6 months, and the tumor size was determined at least twice. RESULTS: The mean follow-up time was 26.6 ± 18.6 months and mean tumor doubling time was 23.4 ± 16.0 months. Histopathological analysis revealed that 32 of the 34 patients were malignant in pT1aN0M0. Only one patient showed tumor recurrence, who subsequently died due to tumor progression. CONCLUSION: The growth rate of the small renal mass was slow in the majority of our patients. Delayed intervention does not have a detrimental effect on cancer-specific outcomes. Dove Medical Press 2013-05-24 /pmc/articles/PMC3669092/ /pubmed/23737676 http://dx.doi.org/10.2147/CMAR.S44221 Text en © 2013 Sugimoto et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Sugimoto, Koichi
Shimizu, Nobutaka
Oki, Takashi
Nose, Kazuhiro
Nishioka, Tsukasa
Adomi, Shogo
Ohzeki, Takayuki
Esa, Atsunobu
Uemura, Hirotsugu
Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title_full Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title_fullStr Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title_full_unstemmed Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title_short Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
title_sort clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669092/
https://www.ncbi.nlm.nih.gov/pubmed/23737676
http://dx.doi.org/10.2147/CMAR.S44221
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