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Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery
BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during survei...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669092/ https://www.ncbi.nlm.nih.gov/pubmed/23737676 http://dx.doi.org/10.2147/CMAR.S44221 |
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author | Sugimoto, Koichi Shimizu, Nobutaka Oki, Takashi Nose, Kazuhiro Nishioka, Tsukasa Adomi, Shogo Ohzeki, Takayuki Esa, Atsunobu Uemura, Hirotsugu |
author_facet | Sugimoto, Koichi Shimizu, Nobutaka Oki, Takashi Nose, Kazuhiro Nishioka, Tsukasa Adomi, Shogo Ohzeki, Takayuki Esa, Atsunobu Uemura, Hirotsugu |
author_sort | Sugimoto, Koichi |
collection | PubMed |
description | BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during surveillance from January 2000 to December 2011. Radiographic evaluations using computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed at least every 6 months, and the tumor size was determined at least twice. RESULTS: The mean follow-up time was 26.6 ± 18.6 months and mean tumor doubling time was 23.4 ± 16.0 months. Histopathological analysis revealed that 32 of the 34 patients were malignant in pT1aN0M0. Only one patient showed tumor recurrence, who subsequently died due to tumor progression. CONCLUSION: The growth rate of the small renal mass was slow in the majority of our patients. Delayed intervention does not have a detrimental effect on cancer-specific outcomes. |
format | Online Article Text |
id | pubmed-3669092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-36690922013-06-04 Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery Sugimoto, Koichi Shimizu, Nobutaka Oki, Takashi Nose, Kazuhiro Nishioka, Tsukasa Adomi, Shogo Ohzeki, Takayuki Esa, Atsunobu Uemura, Hirotsugu Cancer Manag Res Original Research BACKGROUND: This study was undertaken to investigate the growth rate and clinical outcome of patients with a small renal mass (SRM) after delayed surgery. METHODS: We reviewed the clinical records of 34 patients with SRMs ≤ 4 cm at diagnosis, who underwent delayed surgical intervention during surveillance from January 2000 to December 2011. Radiographic evaluations using computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed at least every 6 months, and the tumor size was determined at least twice. RESULTS: The mean follow-up time was 26.6 ± 18.6 months and mean tumor doubling time was 23.4 ± 16.0 months. Histopathological analysis revealed that 32 of the 34 patients were malignant in pT1aN0M0. Only one patient showed tumor recurrence, who subsequently died due to tumor progression. CONCLUSION: The growth rate of the small renal mass was slow in the majority of our patients. Delayed intervention does not have a detrimental effect on cancer-specific outcomes. Dove Medical Press 2013-05-24 /pmc/articles/PMC3669092/ /pubmed/23737676 http://dx.doi.org/10.2147/CMAR.S44221 Text en © 2013 Sugimoto et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Sugimoto, Koichi Shimizu, Nobutaka Oki, Takashi Nose, Kazuhiro Nishioka, Tsukasa Adomi, Shogo Ohzeki, Takayuki Esa, Atsunobu Uemura, Hirotsugu Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title | Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title_full | Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title_fullStr | Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title_full_unstemmed | Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title_short | Clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
title_sort | clinical outcome of incidentally discovered small renal cell carcinoma after delayed surgery |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669092/ https://www.ncbi.nlm.nih.gov/pubmed/23737676 http://dx.doi.org/10.2147/CMAR.S44221 |
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