Novel alterations in the epigenetic signature of MeCP2-targeted promoters in lymphocytes of Rett syndrome patients

Rett syndrome (RTT) is a neurodevelopmental disorder with neurological symptoms, such as motor disorders and mental retardation. In most cases, RTT is caused by mutations in the DNA binding protein MeCP2. In mice, MeCP2 gene deletion has been reported to result in genome-wide increased histone acety...

Descripción completa

Detalles Bibliográficos
Autores principales: Lilja, Tobias, Wallenborg, Karolina, Björkman, Karin, Albåge, Margareta, Eriksson, Maud, Lagercrantz, Hugo, Rohdin, Malin, Hermanson, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669117/
https://www.ncbi.nlm.nih.gov/pubmed/23348913
http://dx.doi.org/10.4161/epi.23752

Ejemplares similares

Ejemplares similares