A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression

Brain cellular heterogeneity may bias cell type specific DNA methylation patterns, influencing findings in psychiatric epigenetic studies. We performed fluorescence activated cell sorting (FACS) of neuronal nuclei and Illumina HM450 DNA methylation profiling in post mortem frontal cortex of 29 major...

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Detalles Bibliográficos
Autores principales: Guintivano, Jerry, Aryee, Martin J., Kaminsky, Zachary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669121/
https://www.ncbi.nlm.nih.gov/pubmed/23426267
http://dx.doi.org/10.4161/epi.23924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669121/
https://www.ncbi.nlm.nih.gov/pubmed/23426267
http://dx.doi.org/10.4161/epi.23924

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