Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia

The objectives of this study were to identify tissue-specific differentially methylated regions (T-DMR’s) in the folate transport genes in placental tissue compared with leukocytes, and from placental tissues obtained from normal infants or with neural tube defects (NTDs). Using pyrosequencing, we d...

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Detalles Bibliográficos
Autores principales: Farkas, Sanja A., Böttiger, Anna K., Isaksson, Helena S., Finnell, Richard H., Ren, Aiguo, Nilsson, Torbjörn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669122/
https://www.ncbi.nlm.nih.gov/pubmed/23417011
http://dx.doi.org/10.4161/epi.23988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669122/
https://www.ncbi.nlm.nih.gov/pubmed/23417011
http://dx.doi.org/10.4161/epi.23988

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