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Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia
The objectives of this study were to identify tissue-specific differentially methylated regions (T-DMR’s) in the folate transport genes in placental tissue compared with leukocytes, and from placental tissues obtained from normal infants or with neural tube defects (NTDs). Using pyrosequencing, we d...
Autores principales: | Farkas, Sanja A., Böttiger, Anna K., Isaksson, Helena S., Finnell, Richard H., Ren, Aiguo, Nilsson, Torbjörn K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669122/ https://www.ncbi.nlm.nih.gov/pubmed/23417011 http://dx.doi.org/10.4161/epi.23988 |
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